Progetti sostenuti

Grazie alle donazioni ricevute, la Fondazione Synapsis sostiene nel 2018 un totale di 29 progetti di ricerca nelle università e istituti di ricerca svizzeri:

 

«Highly sensitive microfluidic assays for quantification of soluble oligomers and diagnostic biomarkers in Alzheimer’s disease»
Prof. Paolo Arosio, ETH Zürich


«Targeted reverse chemical genetics approach to study the role of CREBBP/p300 in Alzheimer’s disease»
Prof. Amedeo Caflisch, Universität Zürich


«Cause and consequence of Parkinson's disease in the midbrain locomotor command center»
Dr. Maria Soledad Esposito, Friedrich Miescher Institut Basel


«The role of the endoplasmic reticulum-mitochondria coupling in Taurelated neurodegenerative diseases»
Dr. Amandine Grimm, Universität Basel


«The factor XII-driven contact system as a new therapeutic target in Alzheimer's disease»
Prof. Jan Klohs, Universität Zürich und ETH Zürich


«Nuclear Tau in Health and Disease»
Dr. Paolo Paganetti, Neurocenter of Southern Switzerland


«Discovering complex connections between brain energy metabolism and Alzheimer disease: Metabolomics-led system’s wide clinical and experimental study»
Prof. Julius Popp, Geneva University Hospitals (HUG)


«How glial metabolic support impacts Alzheimer’s disease disease pathophysiology»
Dr. Aiman S. Saab, Universität Zürich


«Novel anti-PrP human antibodies for therapy of prion diseases»
Dr. Assunta Senatore, Universität Zürich


«Emotion dysregulation in Alzheimer's patients: a new model based on patients with neurodegenerative loss of the amygdala and hormonal regulation related to personality»
Prof. Ron Stoop, Universität Lausanne

«Single-molecule live-cell imaging of repeat-containing RNAs and proteins in C9orf72-associated FTD/ALS»
Dr. Varun Bhaskar, Friedrich Miescher Institute for Biomedical Research Basel


«Using uncoupling in mitochondria of astrocytes to promote neuroprotection in Alzheimer's disease»
PD Dr. Jean-Yves Chatton, Université de Lausanne


«Impaired immune surveillance in Alzheimer's disease: studies on pre-clinical transgenic models and patient-derived samples»
Dr. Maria Teresa Ferretti, Universität Zürich


«Imaging corticostriatal loop dysfunction during skilled locomotion of Parkinsonian mice»
Prof. Fritjof Helmchen, Universität Zürich


«Mechanistic insights into development of prion induced spongiform phenotype and neurotoxicity»
Dr. Asvin Lakkaraju, Universitätsspital Zürich


«Synaptic pruning by dysfunctional microglia in the pathogenesis of neurodegeneration»
Dr. Rosa Chiara Paolicelli, Universität Zürich


«Impact of lymphatic outflow in the brain during aging and neurodegenerative disorders»
Prof. Steven T. Proulx, ETH Zürich


«PM20D1 function in Alzheimer's disease»
Dr. Jose Vicente Sanchez Mut, EPFL


«A novel approach to study the progression of neurodegenerative diseases: investigating the young brain to understand the old»
Dr. Silvia Sorce, Universität Zürich


«Mechanism of the TDP-43 p53 axis in inducing neuronal death in Frontotemporal Lobular Degeneration»
Prof. Verdon Taylor, Universität Basel

«Early synaptic dysfunction in HD model: role of GluN3A»
Prof. Camilla Bellone, Université de Lausanne


«New ocular biomarkers for early detection of Alzheimer's disease»
Prof. Jean-Francois Démonet, Centre Leenaards de la Mémoire, CHUV


«Traces towards dementia: Identifying neuronal subpopulations and pathogenic mechanisms at presymptomatic stages of Alzheimer's disease in a new mouse model»
Prof. Johannes Gräff, Brain Mind Institute, EPFL Lausanne


«Elucidating the pathogenic mechanism of small vessel calcification in idiopathic basal ganglia calcification»
Dr. Annika Keller, Universitätsspital Zürich


«Non-invasive multi-modal imaging of the temporal and spatial relations of amyloid-beta, tau pathology, brain connectivity and atrophy in murine Alzheimer`s disease models»
Dr. Ruiqing Ni, ETH Zürich und Universität Zürich


«Mechanisms that govern maturation and disassembly of stress granules»
Prof. Matthias Peter, ETH Zürich


«Role of astrocytic mitochondria in the early stages of Alzheimer disease»
Dr. Kevin Richetin, CHUV Lausanne


«Investigating distance-dependent interplay between local astrocytic Ca2+ signaling and synaptic plasticity in a mouse model of Alzheimer disease»
Dr. Iaroslav Savtchouk, Universität Lausanne


«The Structure of Prionoid Tau Strains»
Prof. Henning Stahlberg, Universität Basel

Indirizzo

Fondazione Synapsis
Ricerca Alzheimer Svizzera RAS
Josefstrasse 92
CH-8005 Zurigo

 

Come raggiungerci

Servizio donazioni
Telefono: +41 (0)44 271 35 11
E-mail: info(at)alzheimer-synapsis.ch

 

Donazioni

Postfinance: 85-678574-7
IBAN: CH31 0900 0000 8567 8574 7 

Donazioni